We present a systematic literature review of 216 publications from 109 different venues assessing the potential of XR technology to serve as not just a visual accessibility aid but also as a tool to study perception and behavior in people with low vision and blind people whose vision was restored with a neuroprosthesis.

We propose HBA-U-Net: a U-Net backbone with hierarchical bottleneck attention to highlight retinal abnormalities that may be important for fovea and optic disc segmentation in the degenerated retina.

We present a phenomenological model that predicts phosphene appearance as a function of stimulus amplitude, frequency, and pulse duration.

We present an explainable artificiall intelligence (XAI) model fit on a large longitudinal dataset that can predict electrode deactivation in Argus II.

We propose to embed biologically realistic models of simulated prosthetic vision in immersive virtual reality so that sighted subjects can act as ‘virtual patients’ in real-world tasks.

We combined deep learning-based scene simplification strategies with a psychophysically validated computational model of the retina to generate realistic predictions of simulated prosthetic vision.

We systematically explored the space of possible implant configurations to make recommendations for optimal intraocular positioning of Argus II.

In this review, we provide an accessible primer to modern modeling approaches and highlight recent data-driven discoveries in the domains of neuroimaging, single-neuron and neuronal population responses, and device neuroengineering.

Brains face the fundamental challenge of extracting relevant information from high-dimensional external stimuli in order to form the neural basis that can guide an organism’s behavior and its interaction with the world. One potential approach to addressing this challenge is to reduce the number of variables required to represent a particular …

We show that the perceptual experience of retinal implant users can be accurately predicted using a computational model that simulates each individual patient’s retinal ganglion axon pathways.

To investigate the effect of axonal stimulation on the retinal response, we developed a computational model of a small population of morphologically and biophysically detailed retinal ganglion cells, and simulated their response to epiretinal electrical stimulation. We found that activation thresholds of ganglion cell somas and axons varied …

The goal of this review is to summarize the vast basic science literature on developmental and adult cortical plasticity with an emphasis on how this literature might relate to the field of prosthetic vision.

pulse2percept is an open-source Python simulation framework used to predict the perceptual experience of retinal prosthesis patients across a wide range of implant configurations.

Using a dimensionality reduction technique known as non-negative matrix factorization, we found that a variety of medial superior temporal (MSTd) neural response properties could be derived from MT-like input features. The responses that emerge from this technique, such as 3D translation and rotation selectivity, spiral tuning, and heading …

We present a cortical neural network model for visually guided navigation that has been embodied on a physical robot exploring a real-world environment. The model includes a rate based motion energy model for area V1, and a spiking neural network model for cortical area MT. The model generates a cortical representation of optic flow, determines the …