We present a systematic literature review of 216 publications from 109 different venues assessing the potential of XR technology to serve as not just a visual accessibility aid but also as a tool to study perception and behavior in people with low vision and blind people whose vision was restored with a neuroprosthesis.

We propose to embed biologically realistic models of simulated prosthetic vision in immersive virtual reality so that sighted subjects can act as 'virtual patients' in real-world tasks.

Novel stimulation strategies can be tested on sighted subjects viewing a simulation of prosthetic vision in virtual/augmented reality.